CAS No.: | 164656-23-9 |
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Formula: | C27h30f6n2o2 |
Grade: | Food Grade B |
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PRODUCT NAME | Dutasteride |
CAS NO. | 164656-23-9 |
PURITY | 99% |
MELTING POINT | 242-250°C |
BOILING POINT | 620.3±55.0 °C |
DENSITY | 1.303±0.06 g/cm3 |
SOLUBILITY | DMSO: soluble2mg/mL, clear |
APPERANCE | White Powder |
APPLICATION | Organic intermediates, biochemical reagents |
USAGE | Similar to finasteride, dutasteride is a competitive and mechanism-based inhibitor not only of type 2 but also of type 1 5α-reductase isoenzymes, with which stable enzyme-NADP adduct complexes are formed, inhibiting the conversion to DHT. The suppression of both type 1 and type 2 isoforms results in greater and more consistent reduction of plasma DHT than that observed for finasteride. The more effective dual inhibition of type 1 and type 2 5α-reductase isoforms lowers circulating DHT to a greater extent than with finasteride and shows advantages in treating BPH and other disease states (e.g., prostate cancer) that are DHT-dependent. |
SOTRAGE | Sealed containers at cool & dry place. Protect from sunlight, moisture and pest infestation. |